NILE
CHEMICALS
NILE
CHEMICALS
SODIUM META ARSENITE MSDS
1. Product Identification Synonyms: Arsenenous acid, Sodium salt; Sodium meta-arsenite CAS No.: 7784-46-5 Molecular Weight: 129.91 Chemical Formula: Na AsO2 Product Codes: 191145 2. Composition/Information on Ingredients Ingredient CAS No Percent Hazardous --------------------------------------- ------------ ------------ --------- Sodium Meta Arsenite 7784-46-5 98 - 100% Yes 3. Hazards Identification ---------------------------------------------------------------------------------------------------------- Health Rating: 4 - Extreme (Poison) Flammability Rating: 0 - None Reactivity Rating: 1 - Slight Contact Rating: 3 - Severe Lab Protective Equip: GOGGLES & SHIELD; LAB COAT & APRON; VENT HOOD; PROPER GLOVES Storage Color Code: Blue (Health) ----------------------------------------------------------------------------------------------------------- Potential Health Effects ---------------------------------- Inhalation: Arsenic may cause inflammation of the mucous membranes with cough and foamy sputum, restlessness, dyspnea, cyanosis, and rales. Symptoms like those from ingestion exposure may follow. May cause pulmonary edema. Ingestion: Arsenic is highly toxic! May cause burning in esophagus, vomiting, and bloody diarrhea. Symptoms of cold and clammy skin, low blood pressure, weakness, headache, cramps, convulsions, and coma may follow. May cause damage to liver and kidneys. A suspected fetal toxin. Death may occur from circulatory failure. Estimated lethal dose 120 milligrams. Skin Contact: May cause irritation, symptoms including redness, itching, and pain. Eye Contact: May cause irritation with itching, burning, watering of eyes; may cause conjunctiva damage. Chronic Exposure: Arsenic on repeated or prolonged skin contact may cause bronzing of the skin, edema, dermatitis, and lesions. Repeated or prolonged inhalation of dust may cause damage to the nasal septum. Chronic exposure from inhalation or ingestion may cause hair and weight loss, a garlic odor to the breath and perspiration, excessive salivation and perspiration, central nervous system damage, hepatitis, gastrointestinal disturbances, cardiovascular damage, and kidney and liver damage. Arsenic compounds are known human carcinogens and may be teratogenic based on effects in laboratory animals. Aggravation of Pre-existing Conditions: No information found. 4. First Aid Measures Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention. Ingestion: Induce vomiting immediately as directed by medical personnel. Never give anything by mouth to an unconscious person. Get medical attention immediately. Skin Contact: Contaminated work clothes should be laundered by individuals who have been informed of the hazards of exposure to this substance. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical attention immediately. Wash clothing before reuse. Thoroughly clean shoes before reuse. Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately. Note to Physician: If emesis if unsuccessful after two doses of Ipecac, consider gastric lavage. Monitor urine arsenic level. Alkalization of urine may help prevent disposition of red cell breakdown products in renal tubular cells. If acute exposure is significant, maintain high urine output and monitor volume status, preferably with central venous pressure line. Abdominal X-rays should be done routinely for all ingestions. Chelation therapy with BAL, followed by n-penicillamine is recommended, but specific dosing guidelines are not clearly established. 5. Fire Fighting Measures Fire: Not considered to be a fire hazard. Explosion: Not considered to be an explosion hazard. Fire Extinguishing Media: Use any means suitable for extinguishing surrounding fire. Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved selfcontained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode. 6. Accidental Release Measures Ventilate area of leak or spill. Wear appropriate personal protective equipment as specified in Section 8. Spills: Sweep up and containerize for reclamation or disposal. Vacuuming or wet sweeping may be used to avoid dust dispersal. US Regulations (CERCLA) require reporting spills and releases to soil, water and air in excess of reportable quantities. The toll free number for the US Coast Guard National Response Center is (800) 424-8802. 7. Handling and Storage Keep in a tightly closed container, stored in a cool, dry, ventilated area. Protect against physical damage. Isolate from incompatible substances. Wear special protective equipment (Sec. 8) for maintenance break-in or where exposures may exceed established exposure levels. Wash hands, face, forearms and neck when exiting restricted areas. Shower, dispose of outer clothing, change to clean garments at the end of the day. Avoid cross-contamination of street clothes. Wash hands before eating and do not eat, drink, or smoke in workplace. Containers of this material may be hazardous when empty since they retain product residues (dust, solids); observe all warnings and precautions listed for the product. 8. Exposure Controls/Personal Protection Airborne Exposure Limits: For Inorganic Arsenic compounds (as As): - OSHA Permissible Exposure Limit (PEL): l0 ug/m3 (TWA), 5 ug/m3(Action Level), cancer hazard. - ACGIH Threshold Limit Value (TLV):0.01 mg/m3 (TWA), A1, confirmed human carcinogen. Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures below the Airborne Exposure Limits. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details. Personal Respirators (NIOSH Approved): If the exposure limit is exceeded and engineering controls are not feasible, a half-face high efficiency particulate respirator (NIOSH type N100 filter) may be worn for up to ten times the exposure limit or the maximum use concentration specified by the appropriate regulatory agency or respirator supplier, whichever is lowest. A full-face piece high efficiency particulate respirator (NIOSH type N100 filter) may be worn up to 50 times the exposure limit, or the maximum use concentration specified by the appropriate regulatory agency or respirator supplier, whichever is lowest. If oil particles (e.g. lubricants, cutting fluids, glycerine, etc.) are present, use a NIOSH type R or P filter. For emergencies or instances where the exposure levels are not known, use a full-facepiece positive-pressure, air-supplied respirator. WARNING: Air-purifying respirators do not protect workers in oxygen-deficient atmospheres. Skin Protection: Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact. Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area. Other Control Measures: Any area where inorganic arsenic is stored, handled, used, etc., must be established as a 'Regulated Area' with controlled access, limited to authorized persons. Containers of inorganic arsenic and Regulated Areas must be labeled to show a CANCER SUSPECT AGENT is present. Eating, drinking, and smoking should not be permitted in areas where solids or liquids containing arsenic or lead compounds are handled, processed, or stored. See OSHA substance-specific standard for more information on personal protective equipment, engineering and work practice controls, medical surveillance, record keeping, and reporting requirements. (arsenic: 29 CFR 1910 .1018; lead: 29 CFR 1910.1025). 9. Physical and Chemical Properties Appearance: Gray-white powder. Odor: Odorless. Solubility: Very soluble in water. Specific Gravity: 1.87 pH: No information found. % Volatiles by volume @ 21C (70F): 0 Boiling Point: 160C (320F) Melting Point:35.5C (97F) Vapor Density (Air=1): No information found. Vapor Pressure (mm Hg): No information found. Evaporation Rate (BuAc=1): No information found. 10. Stability and Reactivity Stability: Stable under ordinary conditions of use and storage. Hygroscopic. Hazardous Decomposition Products: Emits toxic fumes of arsenic when heated to decomposition. Hazardous Polymerization: Will not occur. Incompatibilities: Acids, iron, aluminum and zinc in the presence of water. Conditions to Avoid: Air, moisture, and incompatibles. 11. Toxicological Information Toxicological Data: Sodium arsenite: oral rat LD50: 41 mg/kg; investigated as a mutagen, tumorigen, reproductive effector. Carcinogenicity: For arsenic and inorganic arsenic compounds: Regulated by OSHA as a carcinogen. EPA / IRIS classification: Group A - Known human carcinogen. --------\Cancer Lists\------------------------------------------------------ ---NTP Carcinogen--- Ingredient Known Anticipated IARC Category ------------------------------------ ----- ----------- ------------- Sodium Arsenite (7784-46-5) Yes No 1 12. Ecological Information Environmental Fate: When released into the soil, this material is not expected to biodegrade. When released into the soil, this material may leach into groundwater. When released into the soil, this material is expected to have a half-life of greater than 30 days. This material may bioaccumulate to some extent. Environmental Toxicity: This material is expected to be slightly toxic to aquatic life. The LC50/96- hour values for fish are between 10 and 100 mg/l. 13. Disposal Considerations Whatever cannot be saved for recovery or recycling should be handled as hazardous waste and sent to a RCRA approved waste facility. Processing, use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state and local requirements. 14. Transport Information Domestic (Land, D.O.T.) ----------------------- Proper Shipping Name: RQ, SODIUM ARSENITE, SOLID Hazard Class: 6.1 UN/NA: UN2027 Packing Group: II Information reported for product/size: 500G International (Water, I.M.O.) ----------------------------- Proper Shipping Name: SODIUM ARSENITE, SOLID Hazard Class: 6.1 UN/NA: UN2027 Packing Group: II Information reported for product/size: 500G International (Air, I.C.A.O.) ----------------------------- Proper Shipping Name: SODIUM ARSENITE, SOLID Hazard Class: 6.1 UN/NA: UN2027 Packing Group: II Information reported for product/size: 500G 15. Regulatory Information --------\Chemical Inventory Status - Part 1\--------------------------------- Ingredient TSCA EC Japan Australia ----------------------------------------------- ---- --- ----- --------- Sodium Arsenite (7784-46-5) Yes Yes Yes Yes --------\Chemical Inventory Status - Part 2\--------------------------------- --Canada-- Ingredient Korea DSL NDSL Phil. ----------------------------------------------- ----- --- ---- ----- Sodium Arsenite (7784-46-5) Yes Yes No Yes --------\Federal, State & International Regulations - Part 1\---------------- -SARA 302- ------SARA 313------ Ingredient RQ TPQ List Chemical Catg. ----------------------------------------- --- ----- ---- -------------- Sodium Arsenite (7784-46-5) 1 500* No Arsenic comp --------\Federal, State & International Regulations - Part 2\---------------- -RCRA- -TSCAIngredient CERCLA 261.33 8(d) ----------------------------------------- ------ ------ ------ Sodium Arsenite (7784-46-5) 1 No No Chemical Weapons Convention: No TSCA 12(b): No CDTA: No SARA 311/312: Acute: Yes Chronic: Yes Fire: No Pressure: No Reactivity: No (Pure / Solid) WARNING: THIS PRODUCT CONTAINS A CHEMICAL(S) KNOWN TO THE STATE OF CALIFORNIA TO CAUSE CANCER. Australian Hazchem Code: 2X Poison Schedule: None allocated. WHMIS: This MSDS has been prepared according to the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS contains all of the information required by the CPR. 16. Other Information NILE CHEMICALS. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS. ACCORDINGLY, MALLINCKRODT BAKER, INC. WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS INFORMATION.Product range
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