NILE
CHEMICALS
NILE
CHEMICALS
1.
IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING
Product
identifiers
Product
name : N-Acetyl-L-tyrosine
CAS-No.
: 537-55-3
2.
HAZARDS IDENTIFICATION
Classification
of the substance or mixture
Classification
according to Regulation (EC) No 1272/2008 [EU-GHS/CLP]
Serious
eye damage (Category 1)
Classification
according to EU Directives 67/548/EEC or 1999/45/EC
Risk
of serious damage to eyes.
Label
elements
Labelling
according Regulation (EC) No 1272/2008 [CLP]
Pictogram
Signal
word Danger
Hazard
statement(s)
H318
Causes serious eye damage.
Precautionary
statement(s)
P280
Wear protective gloves/ eye protection/ face protection.
P305
+ P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes.
Remove
contact
lenses, if present and easy to do. Continue rinsing.
Supplemental
Hazard
Statements
none
According
to European Directive 67/548/EEC as amended.
Hazard
symbol(s)
Sigma
- T4446 Page 2 of 6
R-phrase(s)
R41
Risk of serious damage to eyes.
S-phrase(s)
S26
In case of contact with eyes, rinse immediately with plenty of water and
seek
medical advice.
S39
Wear eye/face protection.
Other
hazards - none
3.
COMPOSITION/INFORMATION ON INGREDIENTS
Substances
Formula
: C11H13NO4
Molecular
Weight : 223,23 g/mol
Component
Concentration
N-Acetyl-L-tyrosine
CAS-No.
EC-No.
537-55-3
208-671-3
4.
FIRST AID MEASURES
Description
of first aid measures
General
advice Consult a physician. Show this
safety data sheet to the doctor in attendance.
If
inhaled If breathed in, move person into
fresh air. If not breathing, give artificial respiration. Consult a physician.
In
case of skin contact Wash off with soap and
plenty of water. Consult a physician.
In
case of eye contact Rinse thoroughly with
plenty of water for at least 15 minutes and consult a physician.
If
swallowed Never give anything by mouth to
an unconscious person. Rinse mouth with water. Consult a physician.
Most
important symptoms and effects, both acute and delayed
Indication
of immediate medical attention and special treatment needed
no data available
5.
FIRE-FIGHTING MEASURES
Extinguishing
media
Suitable
extinguishing media
Use
water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special
hazards arising from the substance or mixture
Carbon
oxides, nitrogen oxides (NOx)
Nature
of decomposition products not known.
Carbon
oxides, nitrogen oxides (NOx)
Precautions
for fire-fighters
Wear
self contained breathing apparatus for fire fighting if necessary.
Further
information no data available
6.
ACCIDENTAL RELEASE MEASURES
Personal
precautions, protective equipment and emergency procedures
Use
personal protective equipment. Avoid dust formation. Avoid breathing vapors,
mist or gas. Ensure
adequate
ventilation. Evacuate personnel to safe areas. Avoid breathing dust.
Environmental
precautions Do not let product enter
drains.
Methods
and materials for containment and cleaning up Pick
up and arrange disposal without creating dust. Sweep up and shovel. Keep in
suitable, closed
containers
for disposal.
Reference
to other sections For disposal see section
13.
7.
HANDLING AND STORAGE
Precautions
for safe handling
Avoid
formation of dust and aerosols.
Provide
appropriate exhaust ventilation at places where dust is formed.Normal measures
for preventive fire
protection.
Conditions
for safe storage, including any incompatibilities
Store
in cool place. Keep container tightly closed in a dry and well-ventilated place.
Specific
end uses
no
data available
8.
EXPOSURE CONTROLS/PERSONAL PROTECTION
Control
parameters
Components
with workplace control parameters
Exposure
controls
Appropriate
engineering controls
Handle
in accordance with good industrial hygiene and safety practice. Wash hands
before breaks and at
the
end of workday.
Personal
protective equipment
Eye/face
protection
Face
shield and safety glasses Use equipment for eye protection tested and approved
under
appropriate
government standards such as NIOSH (US) or EN 166(EU).
Skin
protection
Handle
with gloves. Gloves must be inspected prior to use. Use proper glove removal
technique
(without
touching glove's outer surface) to avoid skin contact with this product. Dispose
of
contaminated
gloves after use in accordance with applicable laws and good laboratory
practices.
Wash
and dry hands.
The
selected protective gloves have to satisfy the specifications of EU Directive
89/686/EEC and the
standard
EN 374 derived from it.
Body
Protection
Complete
suit protecting against chemicals, The type of protective equipment must be
selected
according
to the concentration and amount of the dangerous substance at the specific
workplace.
Respiratory
protection
Where
risk assessment shows air-purifying respirators are appropriate use a full-face
particle
respirator
type N100 (US) or type P3 (EN 143) respirator cartridges as a backup to
engineering
controls.
If the respirator is the sole means of protection, use a full-face supplied air
respirator. Use
respirators
and components tested and approved under appropriate government standards such
as
NIOSH
(US) or CEN (EU).
Sigma
- T4446 Page 4 of 6
9.
PHYSICAL AND CHEMICAL PROPERTIES
Information
on basic physical and chemical properties
a)
Appearance Form: solid
Colour:
white
b)
Odour no data available
c)
Odour Threshold no data available
d)
pH no data available
e)
Melting/freezing point Melting point/range: 149 - 152 °C
f)
Initial boiling point and
boiling
range
no
data available
g)
Flash point no data available
h)
Evaporation rate no data available
i)
Flammability (solid, gas) no data available
j)
Upper/lower
flammability
or
explosive
limits
no
data available
k)
Vapour pressure no data available
l)
Vapour density no data available
m)
Relative density no data available
n)
Water solubility no data available
o)
Partition coefficient: noctanol/
water
no
data available
p)
Autoignition
temperature
no
data available
q)
Decomposition
temperature
no
data available
r)
Viscosity no data available
s)
Explosive properties no data available
t)
Oxidizing properties no data available
Other
safety information
no
data available
10.
STABILITY AND REACTIVITY
Reactivity
no
data available
Chemical
stability
no
data available
Possibility
of hazardous reactions
no
data available
Conditions
to avoid
no
data available
Incompatible
materials
Strong
oxidizing agents
Hazardous
decomposition products
Other
decomposition products - no data available
Sigma
- T4446 Page 5 of 6
11.
TOXICOLOGICAL INFORMATION
Information
on toxicological effects
Acute
toxicity no data available
Skin
corrosion/irritation
Serious
eye damage/eye irritation Eyes
- rabbit - Severe eye irritation Remarks: Severe eye irritation
Respiratory
or skin sensitization no data available
Germ
cell mutagenicity no data available
Carcinogenicity
IARC: No component of this product present
at levels greater than or equal to 0.1% is identified as
probable,
possible or confirmed human carcinogen by IARC.
Reproductive
toxicity no data available
Specific
target organ toxicity - single exposure no
data available
Specific
target organ toxicity - repeated exposure no
data available
Aspiration
hazard no data available
Potential
health effects Inhalation May be harmful if
inhaled. May cause respiratory tract irritation.
Ingestion
May be harmful if swallowed.
Skin
May be harmful if absorbed through skin.
May cause skin irritation.
Eyes
Causes eye burns.
Additional
Information RTECS: Not available
12.
ECOLOGICAL IN FORMATION
Toxicity
no data available
Persistence
and degradability no data available
Bioaccumulative
potential no data available
Mobility
in soil no data available
Results
of PBT and vPvB assessment no data
available
Other
adverse effects no data available
13.
DISPOSAL CONSIDERATIONS
Waste
treatment methods
Product
Offer surplus and non-recyclable solutions
to a licensed disposal company. Contact a licensed professional
waste
disposal service to dispose of this material. Dissolve or mix the material with
a combustible solvent
and
burn in a chemical incinerator equipped with an afterburner and scrubber.
Contaminated
packaging Dispose of as unused product.
14.
TRANSPORT INFORMATION
UN-Number
ADR/RID:
- IMDG: - IATA: -
UN
proper shipping name
ADR/RID:
Not dangerous goods
IMDG:
Not dangerous goods
IATA:
Not dangerous goods
Transport
hazard class(es)
ADR/RID:
- IMDG: - IATA: -
Packaging
group
ADR/RID:
- IMDG: - IATA: -
Environmental
hazards
ADR/RID:
no IMDG Marine pollutant: no IATA: no
Special
precautions for users
no
data available
15.
REGULATORY INFORMATION
This
safety datasheet complies with the requirements of Regulation (EC) No.
1907/2006.
Safety,
health and environmental regulations/legislation specific for the substance or
mixture
no
data available
Chemical
Safety Assessment no data available
Nile Chemicals. provides the
information contained herein in good faith but makes no representation as to its
comprehensiveness or accuracy. This document is intended only as a guide to the
appropriate precautionary handling of the material by a properly trained person
using this product. Individuals receiving the information must exercise their
independent judgment in determining its appropriateness for a particular
purpose. NILE CHEMICALS. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS
OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF MERCHANTABILITY,
FITNESS FOR A PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH
HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS. ACCORDINGLY, NILE
CHEMICALS. WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF OR RELIANCE
UPON THIS INFORMATION.
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